Actor John C. Reilly feels f****ing stoked about being Conan O’Brien’s friend.

John sits down with Conan to chat about the Clown Ministry, his most iconic roles, nourishing souls with his live show Mister Romantic, and relating to chimpanzees. Plus, Conan takes live audience questions about his taste in smoothies, starring in a Bollywood movie, and the worst way to celebrate an anniversary.

Get your Conan O'Brien Needs a Friend Quinquennial Celebration vinyl here: https://bit.ly/4dulsXT

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Got a question for Conan? Call our voicemail: (669) 587-2847.

Conan talks to miner Brad from Manitoulin Island about efficient mine design, how deep Conan could bury himself, and which specific mining position Conan would be best suited for.

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Comedian and actor Paul Scheer feels sanguine about being Conan O’Brien’s friend.

Paul sits down with Conan to discuss his new memoir Joyful Recollections of Trauma, creating his own fake video store while at school, awkward celebrity encounters, and working a celebrity impersonator into his wedding ceremony.

For Conan videos, tour dates and more visit TeamCoco.com.

Got a question for Conan? Call our voicemail: (669) 587-2847.

Conan talks to Anthony from Windsor, Ontario about working as a phlebotomist, singing in a metal band, and how Conan’s specific brand of comedy translates in other countries.

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Actress and comedian Tiffany Haddish feels exuberated about being Conan O’Brien’s friend.

Tiffany sits down with Conan once again to discuss her new memoir I Curse You With Joy, her surprisingly scandalous association with the movie Face/Off, working background on every show imaginable, re-investing in South Central LA properties, and more.

For Conan videos, tour dates and more visit TeamCoco.com.

Got a question for Conan? Call our voicemail: (669) 587-2847.

After his viral appearance on Hot Ones, Conan is joined by Dr. Jose Arroyo for a medical follow-up.

Conan sits down with musician Brian Setzer for a deep dive conversation about his trademark blend of rockabilly and big band as well as the songs that inspired him.

Follow along with the full list of songs here:

Somethin’ Else (Eddie Cochran)

Be Bop A-Lula (Gene Vincent and The Blue Caps)

She Loves You (The Beatles)

Comedian Taylor Tomlinson feels thrilled about being Conan O’Brien’s friend.

Taylor sits down with Conan once more to discuss her late-night show After Midnight, practicing reading off a teleprompter, useless advice from Stephen Colbert, and why entertainment is the best field for a workaholic. Plus, Conan goes behind the scenes of his viral Hot Ones experience, and later, Sona and Matt catch up on the street as they hunt for their respective cars.

For Conan videos, tour dates and more visit TeamCoco.com.

Got a question for Conan? Call our voicemail: (669) 587-2847.